Publications - cysticfibrosis

PUBLICATIONS:

  1. Bobis-Wozowicz S, Paw M. (2024) Transcriptional orchestration of EMT: Unraveling novel molecular targets in pulmonary fibrosis. Mol Ther. 32(11):3765-3767. https://doi.org/10.1016/j.ymthe.2024.10.012
  2. Bobis-Wozowicz S, Ferdek PE. (2024) Harnessing extracellular vesicles for pancreatic fibrosis therapy. Mol Ther. 32(8):2441-2443. https://doi.org/10.1016/j.ymthe.2024.07.004.
  3. Ciesielska P, Lasota S, Bobis-Wozowicz S, Madeja Z. (2024) The role of TGF-β in the electrotactic reaction of mouse 3T3 fibroblasts in vitro. Acta Biochim Pol. 71:12993. https://doi.org/10.3389/abp.2024.12993.
  4. Bobis-Wozowicz S, Paw M, Sarna M, Kędracka-Krok S, Nit K, Błażowska N, Dobosz A, Hammad R, Cathomen T, Zuba-Surma E, Tyszka-Czochara M, Madeja Z. (2024) Hypoxic extracellular vesicles from hiPSCs protect cardiomyocytes from oxidative damage by transferring antioxidant proteins and enhancing Akt/Erk/NRF2 signaling. Cell Commun Signal. 22(1):356. https://doi.org/10.1186/s12964-024-01722-7.
  5. Basso M, Gori A, Nardella C, Palviainen M, Holcar M, Sotiropoulos I, Bobis-Wozowicz S, D'Agostino VG, Casarotto E, Ciani Y, Suetsugu S, Gualerzi A, Martin-Jaular L, Boselli D, Kashkanova A, Parisse P, Lippens L, Pagliuca M, Blessing M, Frigerio R, Fourniols T, Meliciano A, Fietta A, Fioretti PV, Soroczyńska K, Picciolini S, Salviano-Silva A, Bergese P, Zocco D, Chiari M, Jenster G, Waldron L, Milosavljevic A, Nolan J, Monopoli MP, Witwer KW, Bussolati B, Di Vizio D, Falcon Perez J, Lenassi M, Cretich M, Demichelis F. (2024) International Society for Extracellular Vesicles Workshop. QuantitatEVs: multiscale analyses, from bulk to single extracellular vesicle. J Extracell Biol. 3(1):e137. https://doi.org/10.1002/jex2.137.
  6. Łabędź-Masłowska A, Vergori L, Kędracka-Krok S, Karnas E, Bobis-Wozowicz S, Sekuła-Stryjewska M, Sarna M, Andriantsitohaina R, Zuba-Surma EK. (2024) Mesenchymal stem cell-derived extracellular vesicles exert pro-angiogenic and pro-lymphangiogenic effects in ischemic tissues by transferring various microRNAs and proteins including ITGa5 and NRP1. J Nanobiotechnology. 22(1):60. https://doi.org/10.1186/s12951-024-02304-y
  7. Welsh JA, Goberdhan DCI, O'Driscoll L, Buzas EI, Blenkiron C, Bussolati B, Cai H, Di Vizio D, Driedonks TAP, Erdbrügger U, Falcon-Perez JM, Fu QL, Hill AF, Lenassi M, Lim SK, Mahoney MG, Mohanty S, Möller A, Nieuwland R, Ochiya T, Sahoo S, Torrecilhas AC, Zheng L, Zijlstra A, Abuelreich S, Bagabas R, Bergese P, Bridges EM, Brucale M, Burger D, Carney RP, Cocucci E, Crescitelli R, Hanser E, Harris AL, Haughey NJ, Hendrix A, Ivanov AR, Jovanovic-Talisman T, Kruh-Garcia NA, Ku'ulei-Lyn Faustino V, Kyburz D, Lässer C, Lennon KM, Lötvall J, Maddox AL, Martens-Uzunova ES, Mizenko RR, Newman LA, Ridolfi A, Rohde E, Rojalin T, Rowland A, Saftics A, Sandau US, Saugstad JA, Shekari F, Swift S, Ter-Ovanesyan D, Tosar JP, Useckaite Z, Valle F, Varga Z, van der Pol E, van Herwijnen MJC, Wauben MHM, Wehman AM, Williams S, Zendrini A, Zimmerman AJ; MISEV Consortium; Théry C, Witwer KW. (2024) Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches. J Extracell Vesicles. 13(2):e12404. https://doi.org/10.1002/jev2.12404.
  8. Kmiotek-Wasylewska K, Łabędź-Masłowska A, Bobis-Wozowicz S, Karnas E, Noga S, Sekuła-Stryjewska M, Woźnicka O, Madeja Z, Dawn B, Zuba-Surma EK. (2024) Induced pluripotent stem cell-derived extracellular vesicles enriched with miR-126 induce proangiogenic properties and promote repair of ischemic tissue. FASEB J. 38(2):e23415. https://doi.org/10.1096/fj.202301836R.
  9. Lasota S, Zimolag E, Bobis-Wozowicz S, Pilipiuk J, Madeja Z.(2024) The dynamics of the electrotactic reaction of mouse 3T3 fibroblasts. Biochim Biophys Acta Mol Cell Res.1871(2):119647. https://doi.org/10.1016/j.bbamcr.2023.119647.
  10. Paw M, Kusiak AA, Nit K, Litewka JJ, Piejko M, Wnuk D, Sarna M, Fic K, Stopa KB, Hammad R, Barczyk-Woznicka O, Cathomen T, Zuba-Surma E, Madeja Z, Ferdek PE, Bobis-Wozowicz S. (2023) Hypoxia enhances anti-fibrotic properties of extracellular vesicles derived from hiPSCs via the miR302b-3p/TGFβ/SMAD2 axis. BMC Med. 21(1):412. https://doi.org/10.1186/s12916-023-03117-w.
  11. Kmiotek-Wasylewska K*, Bobis-Wozowicz S*, Karnas E, Orpel M, Woźnicka O, Madeja Z, Dawn B, Zuba-Surma EK. (2023) Anti-inflammatory, Anti-fibrotic and Pro-cardiomyogenic Effects of Genetically Engineered Extracellular Vesicles Enriched in miR-1 and miR-199a on Human Cardiac Fibroblasts. Stem Cell Rev Rep. 19(8):2756-2773. https://doi.org/10.1007/s12015-023-10621-2.
  12. Bobis Wozowicz S, Marbán E. (2022) Editorial: Extracellular Vesicles as Next Generation Therapeutics. Front Cell Dev Biol. 10:919426. https://doi.org/10.3389/fcell.2022.919426.
  13. Paw M, Wnuk D, Nit K, Bobis-Wozowicz S, Szychowski R, Ślusarczyk A, Madeja Z, Michalik M. (2021) SB203580-A Potent p38 MAPK Inhibitor Reduces the Profibrotic Bronchial Fibroblasts Transition Associated with Asthma. Int J Mol Sci.22(23):12790. https://doi.org/10.3390/ijms222312790.
  14. Nit K, Tyszka-Czochara M, Bobis-Wozowicz S. (2021) Oxygen as a Master Regulator of Human Pluripotent Stem Cell Function and Metabolism. J Pers Med. 11(9):905. https://doi.org/10.3390/jpm11090905.
  15. Karnas E, Sekuła-Stryjewska M, Kmiotek-Wasylewska K, Bobis-Wozowicz S, Ryszawy D, Sarna M, Madeja Z, Zuba-Surma EK.(2021) Extracellular vesicles from human iPSCs enhance reconstitution capacity of cord blood-derived hematopoietic stem and progenitor cells. Leukemia. 35(10):2964-2977. https://doi.org/10.1038/s41375-021-01325-y.
  16. Gawrys O, Rak M, Baranowska I, Bobis-Wozowicz S, Szaro K, Madeja Z, Swiezewska E, Masnyk M, Chmielewski M, Karnas E, Kompanowska-Jezierska E. (2021) Polyprenol-Based Lipofecting Agents for In Vivo Delivery of Therapeutic DNA to Treat Hypertensive Rats. Biochem Genet. 59(1):62-82. https://doi.org/10.1007/s10528-020-09992-9.
  17. Piejko M, Radziun K, Bobis-Wozowicz S, Waligórska A, Zimoląg E, Nessler M, Chrapusta A, Madeja Z, Drukała J. (2020) Adipose-Derived Stromal Cells Seeded on Integra® Dermal Regeneration Template Improve Post-Burn Wound Reconstruction. Bioengineering (Basel). 7(3):E67. https://doi.org/10.3390/bioengineering7030067.
  18. Paśko P, Tyszka-Czochara M, Trojan S, Bobis-Wozowicz S, Zagrodzki P, Namieśnik J, Haruenkit R, Poovarodom S, Pinsirodom P, Gorinstein S. (2019) Glycolytic genes expression, proapoptotic potential in relation to the total content of bioactive compounds in durian fruits. Food Res Int, 125, 108563. https://doi.org/10.1016/j.foodres.2019.108563.
  19. Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC, Bach JM, Bachurski D, Baharvand H, Balaj L, Baldacchino S, Bauer NN, Baxter AA, Bebawy M, Beckham C, Bedina Zavec A, Benmoussa A, Berardi AC, Bergese P, Bielska E, Blenkiron C, Bobis-Wozowicz S, et al. (2018) Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. J Extracell Vesicles. 7(1):1535750. https://doi.org/10.1080/20013078.2018.1535750.
  20. Adamiak M, Cheng G, Bobis-Wozowicz S, Zhao L, Kedracka-Krok S, Samanta A, Karnas E, Xuan YT, Skupien-Rabian B, Chen X, Jankowska U, Girgis M, Sekula M, Davani A, Lasota S, Vincent RJ, Sarna M, Newell KL, Wang OL, Dudley N, Madeja Z, Dawn B, Zuba-Surma EK. (2018) Induced Pluripotent Stem Cell (iPSC)-Derived Extracellular Vesicles Are Safer and More Effective for Cardiac Repair than iPSCs. Circ Res. 122(2):296-309. https://doi.org/10.1161/CIRCRESAHA.117.311769.
  21. Sekuła M, Domalik-Pyzik P, Morawska-Chochół A, Bobis-Wozowicz S, Karnas E, Boruczkowski D, Adamiak M, Madeja Z, Chlopek J, Zuba-Surma E. (2017) Polylactide- and polycaprolactone- based substrates enhance angiogenic potential of human umbilical cord- derived mesenchymal stem cells in vitro - implications for cardiovascular repair. Mater Sci Eng C Mater Biol Appl. 1;77:521-533. https://doi.org/10.1016/j.msec.2017.03.281.
  22. Bobis-Wozowicz S, Kmiotek K, Kania K, Karnas E, Labedz-Maslowska A, Sekula M, Kedracka-Krok S, Kolcz J, Boruczkowski D, Madeja Z, Zuba-Surma EK. (2017) Diverse impact of xeno-free conditions on biological and regenerative properties of hUC-MSCs and their extracellular vesicles. J Mol Med (Berl). 95(2):205-220. https://doi.org/10.1007/s00109-016-1471-7.
  23. Labedz-Maslowska A, Kamycka E, Bobis-Wozowicz S, Madeja Z, Zuba-Surma EK. (2016) Identification of New Rat Bone Marrow-Derived Population of Very Small Stem Cell with Oct-4A and Nanog Expression by Flow Cytometric Platforms. Stem Cells Int; 2016:5069857. https://doi.org/10.1155/2016/5069857.
  24. Ordovás L, Boon R, Pistoni M, Chen Y, Wolfs E, Guo W, Sambathkumar R, Bobis-Wozowicz S, Helsen N, Vanhove J, Berckmans P, Cai Q, Vanuytsel K, Eggermont K, Vanslembrouck V, Schmidt BZ, Raitano S, Van Den Bosch L, Nahmias Y, Cathomen T, Struys T, Verfaillie CM. (2015) Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition. Stem Cell Reports. 5(5):918-31. https://doi.org/10.1016/j.stemcr.2015.09.004.  
  25. Bobis-Wozowicz S, Kmiotek K, Sekula M, Kedracka-Krok S, Kamycka E, Adamiak M, Jankowska U, Madetko-Talowska A, Sarna M, Bik-Multanowski M, Kolcz J, Boruczkowski D, Madeja Z, Dawn B, Zuba-Surma EK. (2015) Human Induced Pluripotent Stem Cell-Derived Microvesicles Transmit RNAs and Proteins to Recipient Mature Heart Cells Modulating Cell Fate and Behavior. Stem Cells. 33(9):2748-61. https://doi.org/10.1002/stem.2078.
  26. Bobis-Wozowicz S, Galla M, Alzubi J, Kuehle J, Baum C, Schambach A, Cathomen T. (2014) Non-integrating gamma-retroviral vectors as a versatile tool for transient zinc-finger nuclease delivery. Sci Rep. 4:4656. https://doi.org/10.1038/srep04656.
  27. Bobis-Wozowicz S, Millington-Ward S, Zawisz A, Adamus T, Konieczny P, Majka M. (2014) An improved protocol for adipose tissue-derived stem cell isolation: implications for treatment of bone disorders. EJMT. 1(2): 6-21.
  28. Rahman SH, Bobis-Wozowicz S, Chatterjee D, Gellhaus K, Pars K, Heilbronn R, Jacobs R, Cathomen T. (2013) The nontoxic cell cycle modulator indirubin augments transduction of adeno-associated viral vectors and zinc-finger nuclease-mediated gene targeting. Hum Gene Ther. 24(1):67-77. https://doi.org/10.1089/hum.2012.168.
  29. Bobis-Wozowicz S, Miekus K, Wybieralska E, Jarocha D, Zawisz A, Madeja Z, Majka M. (2011) Genetically modified adipose tissue-derived mesenchymal stem cells overexpressing CXCR4 display increased motility, invasiveness, and homing to bone marrow of NOD/SCID mice. Exp Hematol. 39(6):686-696.e4. https://doi.org/10.1016/j.exphem.2011.03.004.
  30. Bobis-Wozowicz S, Osiak A, Rahman SH, Cathomen T. (2011) Targeted genome editing in pluripotent stem cells using zinc-finger nucleases. Methods. 53(4):339-46. https://doi.org/10.1016/j.ymeth.2010.12.019.
  31. Lukasiewicz E, Miekus K, Kijowski J, Drabik G, Wilusz M, Bobis-Wozowicz S, Majka M. (2009) Inhibition of rhabdomyosarcoma's metastatic behavior through downregulation of MET receptor signaling. Folia Histochem Cytobiol. 47(3):485-9. https://doi.org/10.2478/v10042-009-0108-x.
  32. Lukasiewicz E, Miekus K, Kijowski J, Gozdzik J, Wilusz M, Bobis-Wozowicz S, Wiecha O, Majka M. (2009) High anti tumor activity against rhabdomyosarcoma cells and low normal cells cytotoxicity of heat shock protein 90 inhibitors, with special emphasis on 17-[2-(pyrrolidin-1-yl)ethyl]-aminno-17-demethoxygeldanamycin. J Physiol Pharmacol. 60(3):161-6.
  33. Drukała J, Bobis S, Zabińska-Płazak E, Wojas-Pelc A. (2009) Molecular basis of pigmentation disorders in skin diseases. Przegl Lek. 66(3):145-9.
  34. Bobis S, Jarocha D, Majka M. (2006) Mesenchymal stem cells: characteristics and clinical applications. Folia Histochem Cytobiol. 44(4):215-30.